The menopause can manifest through a wide range of signs and symptoms including vasomotor, psychological and genitourinary symptoms. All women undergo the menopause, but not all are affected in the same way or to the same extent. The menopause can be an unsettling and distressing time, affecting women’s well-being, mental health, sexuality, relationships and work. Nurses working in primary care are in a prime position to support women to understand the menopause and offer advice about treatments and lifestyle strategies. The menopause is a midlife event and therefore an opportune time to assess women’s general health and future health needs, investigate and mitigate any risk factors, and diagnose and treat any underlying conditions. This article explores the symptoms and treatments of the menopause and its implications for women’s health and well-being.