Managing community-acquired infections remains an ongoing challenge for community nursing teams. The coronavirus disease 2019 (COVID-19) pandemic meant that community nurses had to ensure they were using evidence-based infection prevention and control measures to limit the effects of the pandemic and maintain patient safety. Community environments can be unpredictable, and compared with acute settings nurses will often lack the appropriate resources when visiting patients in their homes or in residential care. This article outlines effective infection prevention and control measures that nurses can implement in the community, such as the appropriate use of personal protective equipment, optimal hand hygiene, safe waste management and adherence to an aseptic technique.