The implementation of digital health technologies (DHTs) in healthcare organisations has increased significantly following the coronavirus disease 2019 (COVID-19) pandemic. As a result, people with cancer – many of whom are older adults – may be prompted to use DHTs more frequently as part of their care, for example for monitoring treatment-related side effects. Nurses have an important role in addressing patients’ needs in relation to the use of DHTs and explaining how they can benefit from them. Nurses can also assist in encouraging patients to use DHTs, in alleviating their fears about privacy and data security and in reducing digital health inequalities. This article outlines some of the opportunities and challenges presented by the use of DHTs and explains how nurses can facilitate the uptake of DHTs in cancer services, working with patients to ensure that these technologies suit their needs and preferences.