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Randomised controlled trials: an introduction for nurse researchers

01 May 2013

Nurse Researcher


Aim To present an overview of the main components of randomised controlled trials and identify issues for consideration during their design and management....

Developing a nurse-led clinic for patients enrolled in clinical trials

08 April 2011

Cancer Nursing Practice


Successful expansion of local cancer clinical trials portfolios over the past ten years has resulted in increasing demands on clinical staff and resources available...

Using randomised controlled trials (RCTs) to test service interventions: issues of standardisation, selection and generalisability

01 April 2004

Nurse Researcher


The commissioning of healthcare services is increasingly linked to the availability of rigorous evidence of clinical and cost effectiveness. In the current climate,...

Evidence-based practice

01 July 2002

Nurse Researcher

Issues in research

This article provides an insight into the philosophical assumptions underpinning evidence-based practice (EBP). Lois Goding and Keith Edwards believe that EBP has...

Rigour in quantitative research

22 July 2015

Nursing Standard

Art & Science

This article which forms part of the research series addresses scientific rigour in quantitative research. It explores the basis and use of quantitative research and...

Comprehensive evaluation of interventions: eight vital parameters

26 November 2018

Nurse Researcher

Clinical trials

Background It is critically important to determine the effectiveness of an intervention before it can be translated into clinical practice. However, the future...

Strategies for balancing internal and external validity in evaluations of interventions

03 October 2019

Nurse Researcher

Clinical trials

Background Evaluations of interventions should be carefully designed and conducted to maintain a balance between internal and external validity, with the dual goal...

When and how to use factorial design in nursing research

03 December 2020

Nurse Researcher

Quantitative research

Background Quantitative research designs are broadly classified as being either experimental or quasi-experimental. Factorial designs are a form of experimental...

Effect of COVID-19 on cancer research nursing services

22 September 2022

Cancer Nursing Practice

evidence and practice

This service evaluation examined the experiences of adult and children’s cancer research nurses working on early phase cancer clinical trials during the coronavirus...

Improving the recruitment of primary care patients to clinical research studies

02 December 2020

Primary Health Care

research recruitment

This article explores the barriers to primary care research, and considers what is required to conduct research more effectively and to widen opportunities for...