Schizophrenia, its treatment and the lifestyle of patients contribute to high rates of mortality. Patients often have poorer diets, lower rates of physical activity and smoke more than the general population. Such lifestyle choices predispose them to physical health problems and disease. This article explores the impact of poor physical health on mortality in patients with schizophrenia. Suggestions are made for patient education and promotion of a healthy lifestyle to improve the quality of life for patients with the illness.