A donation of whole blood can be processed into red cells, platelets, fresh frozen plasma and cryoprecipitate. This processing permits individual blood components to be given to several different patients and transfusion of appropriate blood components according to the specific needs of the individual. Although blood transfusion may be perceived as a common practice, it is not without risk and all staff should be aware of their roles and responsibilities within this process. To help reduce the risks associated with transfusion, staff must be aware of local policies and procedures, receive the relevant transfusion training, and be assessed as competent.