This article focuses on the recognition and diagnosis of depression in children and young people. Depression in children and young people is underdiagnosed and has been linked to long-term harm. Effective recognition of the condition is crucial in reducing its burden, and supports appropriate management to prevent potential long-term harm. This article explores the causes, risk factors, and signs and symptoms of depression in children and young people, and the role of nurses and other healthcare practitioners in identifying the condition in this patient group.