Half of nurses’ pre-registration training comprises practice placements, on which qualified nurses act as mentors. Standards for professional practice relating to mentoring nursing students are mandatory and set by the Nursing and Midwifery Council. They include: establishing effective working relationships through placement orientation; facilitating and evaluating learning, assessment and accountability; creating an environment conducive to learning; and ensuring students understand the importance of the context of practice, evidence-based practice and leadership. This article discusses related and interdependent aspects of mentoring that are essential for successful practice placements.