Psoriatic arthritis is an inflammatory disease of the joints associated with progressive joint destruction and loss of function. The additional challenge of managing psoriasis can mean patients’ needs differ from those associated with other inflammatory joint conditions. This article discusses the goals of drug treatment and physical therapies in terms of minimising symptoms of the disease. In addition, the psychological effect of this physically debilitating and unpredictable disease is explored. Guidance is offered on how the nurse should address the individual needs of patients and the importance of regular monitoring to ensure safety and efficacy of treatments. The need for effective patient education is emphasised to ensure the person is better able to manage disease progression and any treatment regimens. The nurse’s role should be viewed in the context of the multidisciplinary team to ensure all patient needs are met.