Theophylline overdose: clinical features and management
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Theophylline overdose: clinical features and management

Mark Colbridge Information Officer, National Poisons Information Service (London)

Mark Colbridge discusses the difficulties of establishing a dosage regime for theophylline without inducing toxic effects

Theophylline is a naturally occurring methylxanthine, belonging to the same family as caffeine. Although it has seen a decline in popularity over recent years, it is still prescribed for the treatment of asthma and chronic obstructive pulmonary disease. As well as its bronchodilatory effects, theophylline also has anti-inflammatory and immunomodulatory actions and increases respiratory drive. These findings may well reverse the downward trend in prescribing.

Emergency Nurse. 8, 9, 24-29. doi: 10.7748/en2001.02.8.9.24.c1349

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