Acute lymphoblastic leukaemia (ALL) is the most common form of childhood cancer and a major part of the treatment protocol involves oral chemotherapy taken as an out-patient. In order to achieve maximum therapy with minimum side effects, each child’s full blood count results are monitored weekly and their drug doses are titrated accordingly. One paediatric regional oncology centre has implemented anew approach to this continuing therapy by transferring the responsibility from medical to nursing staff, with very positive results